Suppose we filled a jar with slips of paper with the names of biotech companies that have been around for at least 10 years and with a market cap of at $500 million or more written on them. The chances are quite good that if we pulled a random slip of paper out of that jar, the selected biotech's stock performed reasonably well over the last decade. Of course, the concept of survival of the fittest plays a big factor.
Not every biotech we picked would be a winner, though. Even with an incredible run in recent years for biotech stocks in general, several biotech stocks have lagged well behind their peers. Here are three of the worst performing biotech stocks of the last decade.
1. Lexicon Pharmaceuticals (NASDAQ: LXRX )
Lexicon experienced its heyday in the first few years of the 21st century, but it's pretty much been downhill since then. Shares of the biotech have dropped more than 60% in the past 10 years.
Although it has no commercialized drugs to generate revenue, Lexicon has been able to keep going through the years by forming relationships with larger organizations. For example, Lexicon and Merck (NYSE: MRK ) have worked together for several years to develop biotherapeutic drugs. The partnership with Merck has netted Lexicon $52.5 million in revenue for development.
10 Best Warren Buffett Stocks To Buy For 2015: L&L Energy Inc.(LLEN)
L&L Energy, Inc., through its subsidiaries, engages in the coal mining, clean coal washing, coal coking, and coal wholesaling businesses in the People?s Republic of China. It involves in producing, processing, and selling metallurgical coke used primarily for steel manufacturing; and crushing coal and washing out soluble sulfur compounds with water or other solvents. The company has four coal mines comprising the DaPuAn, SuTsong, Ping Yi, and DaPing mines; three coal washing plants; one coking facility; and coal wholesale and distribution facilities. It also has a financial interest in the Bowie mine, a thermal coal mine located in Paonia, Colorado. The company provides its products to customers in the steel and the electrical/utility industries, as well as to cement factories. L&L Energy, Inc. sells its products directly and through third-party wholesalers. The company was formerly known as L & L International Holdings, Inc. and changed its name to L&L Energy, Inc. in Jan uary 2010. L&L Energy, Inc. was founded in 1995 and is headquartered in Seattle, Washington.
Advisors' Opinion:- [By James E. Brumley]
Well, as it turns out, the snake that bit L&L Energy, Inc. (NASDAQ:LLEN) and Sovereign Lithium Inc. (OTCMKTS:SLCO) didn't end up biting Makism 3D Corp. (OTCMKTS:MDDD). And in retrospect, that's probably how it should be. Indeed, the fact that MDDD didn't even come close to suffering the same fate as SLCO or LLEN did may be the biggest assurance Makism 3D fans could hope for that the company is everything it says it is.
- [By Monica Gerson]
Breaking news
Alcoa (NYSE: AA) is investing US$13 million to expand its wheel manufacturing plant in Europe, to meet growing demand for its lightweight, durable, low-maintenance aluminum truck wheels. To read the full news, click here. L & L Energy (NASDAQ: LLEN) announced today that its Special Independent Committee has appointed Mr. Nicholas Chen, Managing Partner at Pamir Law Group, to replace Mr. Mark Bartlett. To read the full news, click here. Five Prime Therapeutics (NASDAQ: FPRX) and Bristol-Myers Squibb (NYSE: BMY) announced today that they have signed a collaboration agreement for the discovery, development and commercialization of immuno-oncology therapies directed toward targets identified in two undisclosed immune checkpoint pathways using Five Prime's proprietary target discovery platform. To read the full news, click here. First Solar (NASDAQ: FSLR) on Sunday announced the completion of the 1.3MW(DC) solar photovoltaic (PV) power plant at Kitakyushu-shi. Powered by First Solar FS Series 3 Black PV modules, the plant will generate approximately 1,400 MWh of clean and safe solar electricity per year. To read the full news, click here.Posted-In: Credit Suisse US Stock FuturesNews Eurozone Futures Global Pre-Market Outlook Markets
- [By James E. Brumley]
Despite every fiber of my being telling me to not get involved in the schoolyard fight between L&L Energy, Inc. (NASDAQ:LLEN) and apparently one of its enemies (that just so happens to have a short/bearish position in LLEN), I find myself unable to not sound off. A sane and unbiased observation has to be injected into the mix here.
Best Performing Companies To Watch In Right Now: Clearwire Corporation(CLWR)
Clearwire Corporation, through its subsidiaries, provides fourth generation wireless broadband services in the United States. The company builds and operates mobile broadband networks that offer high-speed mobile Internet and residential Internet access services. It serves retail customers through its CLEAR brand. The company markets its products and services directly to consumers, as well as through cellular retailers, consumer electronics stores, satellite television dealers, and computer sales and repair stores; and through company-operated retail outlets. As of December 31, 2011, it had approximately 1.3 million retail and 9.1 million wholesale subscribers. The company is headquartered in Bellevue, Washington. Clearwire Corporation is a subsidiary of Sprint HoldCo LLC.
Advisors' Opinion:- [By Caroline Bennett]
Telecom company Clearwire (NASDAQ: CLWR ) recently revealed its latest budget spreadsheet, and after lackluster results, this may be the company's final quarter among Wall Street stock picks. Clearwire and its largest shareholder, Sprint (NYSE: S ) may soon be great investment opportunities... for another company.
Best Performing Companies To Watch In Right Now: Tropicana Entertainment Inc (TPCA)
Tropicana Entertainment Inc. (TEI) is an owner and operator of regional casino and entertainment properties located in the United States and one casino resort development located on the island of Aruba. TEI�� United States properties include three casinos in Nevada, three casinos in Mississippi, and one casino in each of Indiana, Louisiana and New Jersey. Its properties offer a range of gaming options. TEI�� properties include Tropicana AC in the East; Casino Aztar in Central; Tropicana Laughlin, River Palms and MontBleu in the West; Lighthouse Point, Jubilee, Belle of Baton Rouge, Horizon Vicksburg and Tropicana Aruba in the South and Other.
Tropicana AC
Tropicana Casino and Resort, Atlantic City (Tropicana AC) is situated on a 14-acre site with approximately 660 feet of ocean frontage in Atlantic City, New Jersey. In addition to gaming facilities, the property features The Quarter, a Havana-themed, Las Vegas-style, approximately 200,000 square-foot indoor entertainment and retail center, hosting several restaurants, shops and an IMAX theatre. Other amenities include a 2,000-seat showroom, a full service spa and salon, a health club and indoor pool, a beach and pool bar and approximately 99,000 square feet of meeting and convention space.
Casino Aztar
Casino Aztar Evansville (Casino Aztar) is a casino hotel and entertainment complex in the state of Indiana. Over 60% of Casino Aztar's revenues come from customers within a 50-mile radius. The property's casino operations are located dockside on the three-deck City of Evansville riverboat. Located adjacent to the casino, the Company owns two distinctive hotels: the Casino Aztar Hotel, a 251-room hotel that offers guests a restaurant, conference rooms and banquet facilities; and Le Merigot Hotel, a luxurious 96-room boutique hotel with an upscale martini lounge. A 44,000-square-foot pavilion adjacent to the riverboat features three restaurants, an entertainment lounge, gift shop, coffee shop, pla! yers club and VIP lounge. The District at Casino Aztar includes two restaurants and the Le Merigot Hotel. Casino Aztar also includes a seven-story parking garage, as well as surface parking.
Tropicana Laughlin
Tropicana Laughlin Hotel and Casino (Tropicana Laughlin) is located on an approximately 31-acre site on Casino Drive, Laughlin. The casino at Tropicana Laughlin features a gaming floor. Non-gaming amenities include a heated outdoor swimming pool, seven restaurants, three full service bars, an entertainment lounge with live music, a lounge for high-end players, an 800-seat multi-purpose showroom and concert hall, meeting space, retail stores, an arcade and a covered parking structure. The property features 1,495 hotel rooms.
River Palms
River Palms Hotel and Casino (River Palms) is located on an approximately 35-acre site also on Casino Drive, with approximately 1,300 feet of frontage on the Colorado River. Non-gaming amenities include 1,001 hotel rooms, 10,500 square feet of meeting and convention space, an outdoor pool, fitness center, three restaurants, three full service bars, a showroom, two entertainment lounges with live music and a covered parking structure.
MontBleu
MontBleu Casino Resort & Spa (MontBleu) is situated on approximately 21 acres in South Lake Tahoe, Nevada surrounded by the Sierra Nevada Mountains. In addition to the casino, the property offers guests a choice of three restaurants and various non-gaming amenities, including retail shops, two nightclubs, a 1,500-seat showroom, approximately 14,000 square feet of meeting and convention space, a parking garage, a full service health spa and workout area, an indoor heated lagoon style pool with whirlpool and a 120-seat wedding chapel.
Lighthouse Point
Lighthouse Point Casino (Lighthouse Point) is a 210-foot, three-deck, dockside riverboat located in Greenville, Mississippi. In addition to slot machines, the riverboat inc! ludes a d! eli and bars on each floor while the dockside facility includes a buffet, a bar and 386 onsite surface parking spaces.
Jubilee
Bayou Caddy's Jubilee Casino (Jubilee), a 240-foot dockside riverboat, is located in Greenville. In addition to the casino facilities, the property includes a bar on each floor, a deli and approximately 700 parking spaces. The property also owns and operates the Greenville Inn & Suites, a 41-room suite hotel located less than a mile away, which offers free shuttle service to and from Jubilee and Lighthouse Point.
Belle of Baton Rouge
Belle of Baton Rouge Casino & Hotel (Belle of Baton Rouge) is a dockside riverboat situated on approximately 23 acres on the Mississippi River in the downtown historic district of Baton Rouge, across from the River Center, a 70,000-square-foot convention center. The three-deck, dockside riverboat casino is one of two casino facilities in the Baton Rouge market. Baton Rouge is located 75 miles north of New Orleans. Non-gaming amenities include 300 hotel rooms, 25,000 square feet of meeting and convention space, an outdoor pool, a fitness center, two restaurants, a deli, and an entertainment venue inside a 50,000-square-foot glass atrium that also encloses a tropical lobby.
Horizon Vicksburg
Horizon Vicksburg Casino (Horizon Vicksburg) is a dockside riverboat situated on approximately six acres in downtown Vicksburg, Mississippi. The property features a 297-foot multi-level, antebellum style, dockside riverboat casino housing. Additional amenities include 117 hotel rooms, a restaurant, two covered parking garages as well as additional surface parking. In December 2010, the Company entered into an agreement to sell all of the assets and certain liabilities associated with the operation of Horizon Vicksburg.
Tropicana Aruba
The Company operates timeshare and rental units at Tropicana Aruba Resort & Casino (Tropicana Aruba), a casino resort und! er develo! pment in Noord, Aruba. This resort will have approximately 361 timeshare and rental units, an approximately 16,000 square foot permanent casino, two pools, a swim-up bar & grill, a fitness center and tennis courts, which will be located on approximately 14 acres near Eagle Beach.
Advisors' Opinion:- [By Igor Greenwald]
A majority stake in casino operator Tropicana Entertainment (TPCA) also began with a Chapter 11 restructuring.
From January 1, 2000 to June 10, 2013, Icahn Enterprises has averaged a 20% annual return, multiplying investors' money nearly 12-fold. Berkshire-Hathaway (BRK-B) has managed only a triple over the same span.
Best Performing Companies To Watch In Right Now: Semiconductor Manufacturing International Corporation(SMI)
Semiconductor Manufacturing International Corporation, an investment holding company, engages in the computer-aided design, manufacture, packaging, testing, and trade of integrated circuits. It offers a range of technologies from 0.35μm to 65nm with capabilities that include logic, mixed signal/RF CMOS, high voltage, embedded, flash, EEPROM, and CIS technology. The company also provides portfolio of semiconductor intellectual property (IP) blocks from 0.35um to 65nm to support the design needs of customers; ASIC design services; reference flows; mixed-signal/RF PDKs; and multi-project wafer services. In addition, it involves in the design and manufacture of semiconductor masks; and provides assembly and testing, wafer bumping, and wafer probing/testing services. Further, the company offers marketing related activities; operates convenience stores; and manufactures and trades in solar cell related semiconductor products. Its products are used primarily in mobile, network ing, and wireless local area network applications, as well as in consumer and communications products, including digital television, set-top box, mobile, portable media player, and personal digital assistant applications. The company serves integrated device manufacturers, fables semiconductor companies, and system companies principally in the United States, Europe, and the Asia Pacific. Semiconductor Manufacturing International Corporation was founded in 2000 and is headquartered in Shanghai, the People?s Republic of China.
Advisors' Opinion:- [By Namitha Jagadeesh]
The SMI (SMI) declined 0.1 percent to 8,161.14 at 10:05 a.m. in Zurich. The gauge fell 1.4 percent last week, its first retreat in five weeks. The broader Swiss Performance Index also decreased 0.1 percent today.
- [By Corinne Gretler]
Nestle decreased 2.6 percent to 63 francs, contributing the most to the SMI (SMI)�� drop. Revenue in the first half increased 4.1 percent, excluding acquisitions, divestments and currency shifts. That missed the median estimate of 4.5 percent growth.
- [By Pato Kehoe]
In an attempt to trim costs and increase its operational efficiencies, Estee Lauder�� business strategy last year focused on centralizing its core operating functions, as well as reducing non-profitable stock keeping units. The cost reduction program, Strategic Modernization Initiative (SMI), proved highly efficient, saving the company $781 million in 2013. Furthermore, while the program will continue throughout 2014, management announced that it would be reinvesting a large amount of the cost savings in marketing for its core brands, along with product innovation. In this regard, decentralizing innovation to better adjust to its global customer preferences, is and will continue to be a key strategy in further propelling the beauty giant�� growth.
Best Performing Companies To Watch In Right Now: PGT Inc.(PGTI)
PGT, Inc. engages in the manufacture and supply of residential impact-resistant windows and doors. The company offers impact-resistant products, including heavy-duty aluminum or vinyl frames with laminated glass to provide protection from hurricane-force winds and wind-borne debris. It also provides a range of non-impact-resistant aluminum and vinyl frame windows and doors; Architectural Systems line of products, which offer protection from hurricane-force winds and wind-borne debris for mid-and high-rise buildings; and non-glass vertical and horizontal sliding panels for porch enclosures, such as vinyl-glazed and aluminum-framed products used for enclosing screened-in porches that provide protection from inclement weather. The company markets its products under the WinGuard, PremierVue, PGT Architectural Systems, Eze-Breeze, and SpectraGuard brand names. PGT, Inc. offers its products to residential new construction, and home repair and remodeling end markets through windo w distributors, building supply distributors, window replacement dealers, and enclosure contractors. It operates in the southeastern United States, the Gulf Coast, Coastal mid-Atlantic, the Caribbean, Central America, and Canada. The company was formerly known as JLL Window Holdings, Inc. and changed its name to PGT, Inc. in January 2004. PGT, Inc. was founded in 1980 and is based in North Venice, Florida.
Advisors' Opinion:- [By Seth Jayson]
There's no foolproof way to know the future for PGT (Nasdaq: PGTI ) or any other company. However, certain clues may help you see potential stumbles before they happen -- and before your stock craters as a result.
Best Performing Companies To Watch In Right Now: Eyes on The Go Inc (AXCG)
Eyes on the Go, Inc., incorporated on August 26, 2010, designs, implements, and provides services for the remote real-time monitoring of, and the control of equipment and devices located at, businesses and other facilities via computers, wireless handheld devices and television equipment using the Internet, through its Website, www.eyesonthego.com, or internal communications. As of May 1, 2011, the Company entered into a Plan and Agreement of Merger by and among the Company, Eyes Enterprises, Inc. and its wholly owned subsidiary, and EOTG, under which Enterprises was merged with and into EOTG, with EOTG being the surviving entity. As a result of this merger, the Company changed its name to Eyes on the Go, Inc. and EOTG changed its corporate name to Eyes Enterprises, Inc. On May 11, 2011 the Company completed a Plan and Agreement of Merger with Mutual Exchange Corp. The Company was considered to be the accounting acquirer, and the merger was accounted for as a reverse merger, whereby the Company being the accounting survivor.
Users of the Company�� services can view monitored facilities from video cameras, as well as receive temperature and other data; can remotely control devices, such as thermostats, lights and locks, and can receive e-mail-based alerts of door entries and other events with video clips and of equipment failures and deviations from temperature and other parameters. Its system can also store images and data for review. The Company markets primarily to business owners and managers in the hospitality industry.
The Company competes with Control4 Corporation, SVAT Electronics, Motorola, Inc., iControl Networks, Inc., Mi Casa Verde, Inc. and ADT Security Services, Inc.
Advisors' Opinion:- [By Peter Graham]
Small cap stocks Eyes on The Go Inc (OTCMKTS: AXCG), Quadrant 4 Systems Corp (OTCMKTS: QFOR) and Cloud Security Corp (OTCMKTS: CLDS) were getting attention last week, but all three stocks trended downward on Monday. It should be mentioned that none of these stocks have been overly or heavily paid promotions. So what will these three small cap stocks do on the last trading day of the year and for the rest of this week? Here is a closer look:
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